When prescribed valproic acid, which instruction is essential for the nurse to provide?

When prescribed valproic acid, which instruction is essential for the nurse to provide?

• A. Follow-up blood tests are necessary while on this medication
• B. The extended-release tablet can be crushed if necessary for ease of swallowing
• C. Tachycardia and upset stomach are common side effects
• D. Consumption of a moderate amount of alcohol is safe if the medication is taken in the morning

Answer: (A)

When a patient is prescribed valproic acid, it is essential to emphasize the importance of follow-up blood tests. This medication has a narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small. Regular blood tests are necessary to monitor medication levels, as well as liver function and platelet counts, given that valproic acid can cause potential liver damage and affect blood parameters. This monitoring helps ensure that the medication remains effective and reduces the risk of adverse effects. The other options, while they may contain valid information, do not represent essential instructions. The option regarding crushing the extended-release tablet is inaccurate, as doing so could alter the release mechanism of the medication, leading to increased side effects or reduced efficacy. Discussing common side effects like tachycardia and upset stomach is helpful, but it does not encompass the critical monitoring aspect necessary while on this medication. Lastly, recommending the safe consumption of alcohol contradicts the advice typically given to patients on medications such as valproic acid, where alcohol can significantly increase the risk of side effects, such as liver toxicity. Thus, the essential instruction revolves around the need for follow-up blood tests to ensure patient safety and medication effectiveness.

When a patient is prescribed valproic acid, it is essential to emphasize the importance of follow-up blood tests. This medication has a narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small. Regular blood tests are necessary to monitor medication levels, as well as liver function and platelet counts, given that valproic acid can cause potential liver damage and affect blood parameters. This monitoring helps ensure that the medication remains effective and reduces the risk of adverse effects.

The other options, while they may contain valid information, do not represent essential instructions. The option regarding crushing the extended-release tablet is inaccurate, as doing so could alter the release mechanism of the medication, leading to increased side effects or reduced efficacy. Discussing common side effects like tachycardia and upset stomach is helpful, but it does not encompass the critical monitoring aspect necessary while on this medication. Lastly, recommending the safe consumption of alcohol contradicts the advice typically given to patients on medications such as valproic acid, where alcohol can significantly increase the risk of side effects, such as liver toxicity. Thus, the essential instruction revolves around the need for follow-up blood tests to ensure patient safety and medication effectiveness.